Parkinson's Disease - The Brain on Fire
Mounting evidence is lending further support to the concept that various brain degenerative disorders are fundamentally caused by inflammation - the same process with which we are so familiar when dealing with an arthritic knee, skin irritation, and various inflammatory bowel disorders. While inflammation is typically accompanied by pain when it occurs in parts of the body outside the brain, the brain itself is pain insensitive so we remain unaware that inflammation is at work damaging delicate brain cells.
New research confirms the presence of specific chemical mediators of inflammation as well as inflammatory cells in the area of maximum degeneration in the brains of Parkinson's patients as described in a recent review appearing in Annals of Neurology (Entrez-PubMed). This knowledge paves the way for new strategies to both reduce the risk of this devastating disease as well as slowing its progress. The role of inflammation in neurodegenerative diseases as well as unique therapeutic strategies based on this model will be the subject of my presentation at The 1st International Conference on The Integrative Medical Approach to the Prevention of Alzheimer's Disease Alzheimer's Prevention Foundation Conference in October, 2003.
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